Apolipoprotein A-I

An extremely sensitive marker for the measurement of Apo A-I

Clinical Significance

APO A-I may be measured in patients with a personal or family history of high concentrations of lipids and/or premature CHD. It may be requested to find out the cause of high lipid levels and/or a suspected disorder that is causing a deficiency in APO A-I. APO A-I can be used with APO B-100 to check your ratio of “good” to “bad” cholesterol

Apo A-I is produced in the liver and intestines and is the main protein component of HDL Cholesterol.  The main role of Apo A-I involves reverse cholesterol transport – it removes excess cholesterol from the tissues and transports it to the liver for removal.  Apo A-I can be described as non-atherogenic; it shows an inverse relationship to cardiovascular risk

The A Apolipoproteins are the main form of protein found in High Density Lipoproteins (HDL). The main role of APO A-I is in the activation of Lecithin Cholesterol Acyl Transferase (LCAT) and removal of free cholesterol from extra hepatic tissues.  APO A-I may therefore be described as non atherogenic, showing an inverse relationship to cardiovascular risk.

Key Features of Randox Apolipoprotein Apo A-I

 

Quality Control

RIQAS EQA Scheme

 

Quality Control

 

Calibrators

 

Ordering information

LP2116 R1 4 x 40ml (c) R2 4 x 17ml
LP2866 160T (Dimension)
LP2989 R1 4 x 60ml (c) R2 4 x 36ml
LP3838 R1 4 x 30ml R2 4 x 12ml
LP8007 R1 2 x 10ml R2 2 x 4.9ml

Applications are available for a large range of clinical chemistry analysers. Contact us for more information.


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