An extremely sensitive marker for the measurement of Apo A-II
Increased levels of Apo A-II appear to promote atherosclerosis by displacing Apo A-I in HDL and inhibiting reverse cholesterol transport.
Apolipoprotein A-II is a major constituent of High Density Lipoprotein (HDL) particles and plays an important role in reverse cholesterol transport and lipid metabolism. The distribution of Apo A-I in the HDL is primarily determined by the production rate of Apo A-II. Increased production of Apo A-II promotes atherosclerosis by decreasing the proportion of anti-atherogenic HDL containing Apo A-I.
Apo A-II is synthesised mainly in the liver and modulates lipoprotein lipase and hepatic triglyceride lipase. It also acts as a co-factor for Lecithin cholesterol acetyltransferase which is involved in lipoprotein processing.
Key Features of Randox Apolipoprotein A-II
- Wide measuring range – With a measuring range of 6.50-233 mg/dl, it will comfortably detect levels outside of the healthy range of 120-176mg/dl
- Excellent stability – Stable to expiry when stored at 2-8°C
- Liquid ready-to-use reagents – The Randox Apolipoprotein A-I reagent comes in a liquid format which is more convenient, and can also help reduce the risk of errors occurring
- Lipid Controls
- Lipid Calibrators
- Calibrator included in LP2116 and LP2989
LP3867R1 2 x 11mlR2 2 x 5ml
Applications are available for a large range of clinical chemistry analysers. Contact us for more information.