Apolipoprotein C-III

A highly accurate test for the measurement of Apo C-III

Clinical Significance

Apo C-III levels have been reported higher in many pathological conditions including Type 2 diabetes, hyperbilirubinemia, kidney deficiency and decreased thyroid function. Factors that influence Apo C-III levels are gender, age, menopause and genetic polymorphisms in the Apo C-III gene.

Apolipoprotein C-III is a 79 amino acid protein synthesised mainly in the liver and to a lesser extent in the intestine. Apo C-III circulates in the plasma in association with triglyceride rich lipoproteins and HDL. Apo C-III modulates the uptake of triglyceride-rich lipoproteins by the LDL receptor related protein through inhibition of lipoprotein lipase. Elevated levels of Apo C-III are associated with both primary and secondary hypertriglyceridemia.

Key Features of Randox Apolipoprotein C-III

 

Quality Control

Quality Control

 

Calibrators

 

Ordering information

LP3865R1 2 x 11mlR2 2 x 5ml

Applications are available for a large range of clinical chemistry analysers. Contact us for more information.


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