sLDL Cholesterol

Quick and accurate testing for the risk of myocardial infarction (MI)

Clinical Significance

Research has shown individuals with a predominance of sLDL have a 3-fold increased risk of myocardial infarction (MI). Elevated levels of sLDL are associated with a sedentary lifestyle, a diet high in saturated fat, insulin resistance, pre-diabetes and genetic disposition. Measurement of sLDL allows the clinician to get a more comprehensive picture of lipid risk factors and tailor treatment accordingly. Reducing LDL levels reduce the risk of both CVD and MI.

It is recommended a patient get tested when:

 

sLDL is a subtype of LDL cholesterol. There are two main types of LDL which vary in size through genetic determination and dietary lipid intake, ranging from small and dense to large and buoyant LDL. All LDLs transport triglycerides and cholesterol to the tissues but their atherogenesis varies according to size. Smaller particles such as sLDL more readily permeate the inner arterial wall and are more susceptible to oxidation.

Previous tests such as ultracentrifugation and electrophoresis based methods are used for the measurement of sLDL-C but these methods are both laborious and time-consuming.

Randox uses the “Denka Seiken” method which produces results in ten minutes. There are two main reaction steps based on the presence of surfactants and enzymes that selectively react with certain groups of lipoproteins.

Key Features of Randox sLDL Cholesterol

 

Quality Control

RIQAS EQA Scheme

 

Quality Control

 

Calibrators

 

Ordering information

562616R1 1 x 19.8mlR2 1 x 8.6ml

Applications are available for a large range of clinical chemistry analysers. Contact us for more information.


© 2018 Randox Laboratories Ltd. All rights reserved.